Application Note ET-35 ESI and MALDI Tandem Mass Spectrometry of Poly(ethylene imine)s: A Comparison Study for Structural Characterization
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چکیده
ESI-Q-TOF and MALDI-TOF/TOF mass spectrometers were utilized to elucidate the macromolecular structures of linear poly(ethylene imine) (PEI) polymers, which are of importance in gene delivery. A detailed characterization of linear PEIs was performed by tandem mass spectrometry (MS/MS). This study provides important information with regard to the fragmentation mechanism of PEI polymers and the comparison of the tandem mass analysis of these polymers with two different ionization techniques (ESI/MALDI). Application Note ET-35 ESI and MALDI Tandem Mass Spectrometry of Poly(ethylene imine)s: A Comparison Study for Structural Characterization B ru ke r D al to ni cs is c on tin ua lly im pr ov in g its p ro du ct s an d re se rv es t he r ig ht to c ha ng e sp ec ifi ca tio ns w ith ou t no tic e. © B ru ke r D al to ni cs 0 9 -2 01 3, E T35 , 8 70 4 0 61
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